What's to know about myasthenia gravis?

What's to know about 

myasthenia gravis?


Myasthenia gravis is a relatively rare neuromuscular disease in which the voluntary muscles easily become tired and weak because there is a problem with how the nerves stimulate the contraction of muscles. It is an autoimmune disorder.

"Myasthenia gravis" literally means "grave muscle weakness," but many cases are mild, and life expectancy is normal.
The muscles around the eyes tend to be affected first, causing the eyelids to droop. Patients may experience double vision, weakness in the arms and legs, and difficulties chewing, swallowing, speaking, and breathing. Involuntary muscles, such as the heart muscles, are not affected.
Symptoms often worsen with physical activity and improve after resting or a good night's sleep. There is no cure, but treatment can relieve and even remove symptoms.
The condition affects 14 to 20 people in every 100,000 in the United States, or between 36,000 and 60,000 people. It can happen at any age, but it is more likely to affect women before the age of 40 years, and men after the age of 60 years.

Treatment

[woman in wheelchair]

With myasthenia gravis, the limbs can weaken.
There is no cure for myasthenia gravis, but treatment with immunosuppressants or cholinesterase inhibitors can help control symptoms.
Many patients find that with treatment, and adequate sleep and rest, they can carry on with their normal routine.
Medications include:
  • Cholinesterase inhibitors: These improve communication between nerves and muscles, and are effective in patients with mild symptoms of MG.
  • Steroids, such as prednisolone, or immunosuppressants, such as azathioprine, may alter the body's immune system so that it produces fewer of the antibodies that cause MG.
  • It usually takes about 4 weeks for steroids to take effect. Azathioprine may take from 3 to 6 months, but it brings about a significant reduction or complete removal of symptoms.
    In the case of a tumor, the thymus gland may be surgically removed in a thymectomy.
    For patients with severe or life-threatening symptoms, plasmapheresis and immunoglobulin therapy can be administered in the hospital.
    Plasmapheresis involves depleting the body of blood plasma without depleting the body of its blood cells, in order to remove the unwanted antibodies.
    Intravenous immunoglobulin therapy involves injecting the patient with normal antibodies that change the way the immune system acts.
    These treatments are effective, and they work quickly, but the benefits last only a few weeks, so this is a short-term treatment.

  • Prevention

    MG cannot be prevented. However, a person can take steps to stop a flare-up of symptoms or prevent them from developing complications.
    These include practicing careful hygiene to avoid infections, and treating them promptly if they do occur.
    It is also advisable to avoid extreme temperatures and overexertion. Effective stress management can also reduce the frequency and severity of symptoms

Comments

Post a Comment

Popular posts from this blog

Dandruff? There Are 5 Types, So You Might Just Be Treating It Wrong!

Image
Dandruff? There Are 5 Types, So You Might Just Be Treating It Wrong!                                                                It starts slowly. Your black clothes are the first to be banished. Then comes the embarrassment. The awkward dance of your hands with your hair – tucking it behind your ears, rolling it up in a bun, spreading it out strategically to conceal those pesky white flakes that lay beneath. Dandruff. And there are several types of dandruff. Read on. Diagnose Your Dandruff “Eczema, dryness of scalp, infrequent shampooing and a yeast-like fungus are all common causes of the itchiness and dry flakes that define dandruff. To treat this unfortunate condition, it’s best to identify the type of dandruff that may be getting you down,” explains Dr Gray. 1)Dry-skin related dandruff Dandruff caused by dry skin is one of the most common types and occurs mainly in winter, because washing hair with warm water tends to make the scalp dry and flaky. Interes
Read more
Image
Generalized Anxiety Disorder: Causes and Risk Factors                                           There is no singular cause of  generalized anxiety disorder  that has been identified. Evidence has shown that multiple factors are usually at play, influencing the development of GAD. Some of the common factors include things like genetic predisposition, brain chemistry, family background, social influence, and life experiences.                                Brain Structure The limbic system is a collection of brain structures that, among other functions, is involved in the regulation of many of our basic emotional reactions. Although it is generally under the control of the "thinking" part of our brain, it can respond to stimuli on its own as well. Genetics Your genetics may play a role in determining whether or not you will develop GAD. As with many other mental and medical health conditions, we can be genetically predisposed for dev
Read more